I can go into New York and sell out a theatre, but I didn't have to fight my way to get there: I was already a made man from television. I sold out a theatre in London without any TV exposure, just word of mouth and being a good comic, and that was a much bigger sense of accomplishment than just being a guy from telly.

I don't care if people get angry about that, believing the rubbish that vaccinations cause trouble or make the child worse or something. That's not what I believe. I think it's important for me to say.

The difference between comedians and the general public is that we are meant to be funnier. And when you've got politicians giving material so easy that the general public is doing it, what is the necessity of us anymore?

When I was 23, I didn't have much of an interest in politics. All of my interests were in partying and meeting girls and doing stand-up. That's all I cared about. Now, when you have a kid and stuff, you start watching the news and say, 'They shouldn't take money away from this education department.' You start having much more exact opinions.

I'd like to start trying different fields of work. I don't want to be stuck in just comedy, and I'd be interested to try to break into the movie business because it's so much different than television.

If you look at American medical fiction written by doctors, like 'The House of God' by Samuel Shem and 'The Blood of Strangers' by Frank Huyler, both have themes of cynicism and dysfunction running through them that you won't find in 'ER.' You find it in 'Scrubs,' but because that's a comedy, it gets away with it.

In my experience, if people don't have a sense of humor, they are usually not very good scientists, either.

I would love to do a biopic or a situational comedy.