There are physical characteristics which are inherited. These include things like good looks, high intelligence, physical coordination. These attributes contribute to success in life, and success in life is a determinant of optimism.

I've been bothered about time generally and our tripartite division of time into past, present, and future. I think I know what the past is, and I think I know what future is, but I'm really not comfortable with the notion of present.

I'm all for past influences; the question is whether they are deterministic. Freud and the behaviorists argue that what we are at any given moment is billiard balls whose past determines our future course. That doesn't take into account that we are forever generating internal representations of positive futures and choosing among them.

The goal of a life free of dysphoria is a snare and a delusion. A better goal is of good commerce with the world. Authentic happiness, astonishingly, can occur even in the presence of authentic sadness.

While I may never be in remission from cancer, I am currently in remission from an unhealthy relationship to food.

If we had pursued what President Nixon declared in 1970 as the war on cancer, we would have cured many strains. I think Jack Kemp would be alive today. And that research has saved or prolonged many lives, including mine.

Price gouging for drugs that treat cancer in children is simply unconscionable.

To continue to work, to continue to love what you do, is certainly a contributing element to one's longevity and health.