Winning a Nobel Prize isn't about being clever at all. It's about making... at least in physiology or medicine, it's about making discoveries, and you don't have to be clever to make a discovery, I don't think; it just comes up and punches you on the nose.

It's terribly important that you can criticise people's ideas without criticising them, and if they burst into tears, it means that you tend to hold back from getting at the absolute truth.

You don't want to inhibit cell division. You want to inhibit cell division in the cancer cells, and even that is not really where you want to do it. You actually want to destroy the cancer cells, which is a different matter altogether. Just stopping them isn't enough - you really want to kill them.

The idea was to study fertilization in as many different phyla and organisms as possible, using the simplest possible equipment and a microscope. Biochemical approaches were not much in vogue, and running gels impossible at first.