A single human brain has about a hundred million nerve cells... and a computer program that throws light on the mind/brain problem will have to incorporate the deepest insights of biologists, nerve scientists, psychologists, physiologists, linguists, social scientists, and even philosophers.

It is easy to predict that some of the discoveries of research directed towards Grand Challenges - but only the most unexpected ones, and at the most unexpected times - will be the basis of revolutionary improvements in the way that we exploit the power of our future computing devices.

An ultimate joint challenge for the biological and the computational sciences is the understanding of the mechanisms of the human brain, and its relationship with the human mind.

By the time I'm 75 and I have a new hip, and my eyes are laser cleaned of cataracts, I wont think I'm a bionic man. I think that's just how technology works. The posthuman future of humanity will not announce itself; it will just creep up on us.

The march of science and technology does not imply growing intellectual complexity in the lives of most people. It often means the opposite.

I call the blockchain 'the Internet of value' and 'the Internet of trust.' Because everything becomes trustless. It's a big distributed ledger. Think of it like an Excel file that's being maintained and updated and managed by millions of computers around the world.

What has always made IBM a fascinating and compelling place for me is the passion of the company, and its people, to apply technology and scientific thinking to major societal issues.