I studied neuroscience at the cellular level, so I was looking at learning and memory in the visual cortex of rats. Neuroscience mainly exposed me to a way of thinking - about experimentation, about what you believe to be true and how you could prove it - and how to approach things in a methodical manner.

Most of us yearn for really intimate, healthy, in-person relationships. People have a deep desire to be understood, to be told that it's OK, that you're not isolated and broken, that this is part of the human challenge, and that there is hope. The capacity for online interactions to do that is powerful.

Let me think about the people who I care about the most, and how when they fail or disappoint me... I still love them, I still give them chances, and I still see the best in them. Let me extend that generosity to myself.

On street corners everywhere, people are looking at their cell phones, and it's easy to dismiss this as some sort of bad trend in human culture. But the truth is life is being lived there. When they smile - right, you've seen people stop - all of a sudden, life is being lived there, somewhere up in that weird, dense network.

In the scope of a happy life, a messy desk or an overstuffed coat closet is a trivial thing, yet I find - and I hear from other people that they agree - that getting rid of clutter gives a disproportionate boost to happiness.

It's sad that grandkids show up at the end of obituaries, way behind the list of work place achievements, social clubs and survivors. Why last? If you've got grandkids, you know they're first when it comes to the joy in your life.

The happiness of one's own heart alone cannot satisfy the soul; one must try to include, as necessary to one's own happiness, the happiness of others.

Musicians are probably the most uncomfortable people in themselves in the world. Happiness, I think, only exists when you're a child and once you go past 11, unfortunately it's gone.