Especially working in infectious disease, it's very interesting because these infectious diseases, these agents, they evolve over time. So it's very much an arms race and understanding how each changes to protect itself and to continue. And so it's very much this puzzle-solving but with this great urgency and importance in what you find.

At 9, I think I had really gotten into tennis. I liked writing short stories; I loved solving math problems. I was learning a little piano, and I was collecting Garbage Pail Kids cards.

The process of discovery in my field is very incremental. But there are moments when you realize you know something about the world nobody else knows. That's extraordinarily exhilarating.

You get these moments of thrill. There you are, at 3:00 in the morning, and you know something about how we evolved that nobody else in the world knows. It's a thrill of discovery. You make this breakthrough, and you find something. It's this wonderful, wonderful scavenger hunt when you got to the end. It's just so great to be a scientist.

Wellbeing is a notion that entails our values about the good life, and questions of values are not ultimately scientific questions.

When I was in 7th grade, we were all given an exam. It was science and math, and the boys who did well were skipped ahead so that when they got to be juniors or seniors in high school they would be able to go to the local community college and take calculus and physics there. And I wasn't skipped ahead.

From a UX standpoint, the toughest battle is how to make a platform that's really open so kids can use it but has sort of hooks and constraints so it's actually driving towards revealing parts of the world through science or through mathematics.

Don't you see what's at stake here? The ultimate aim of all science to penetrate the unknown. Do you realize we know less about the earth we live on than about the stars and the galaxies of outer space? The greatest mystery is right here, right under our feet.